Studies

CellWell record HH-13423

Indole-3-Carbinol (I3C) suppression of IgG2b-triggered signaling in innate cells involves early suppression of p-Akt.

Deb A; Miceli A; Kaplan BLF

Toxicology and applied pharmacology ยท 2026

In plain language

In an immune signaling study linked to multiple sclerosis research, indole-3-carbinol suppressed IgG2b-triggered Akt phosphorylation in innate immune cells, suggesting a nontoxic anti-inflammatory signaling mechanism worth further study.

Studied in
Animal

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