Studies

CellWell record HH-132146

Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for an Anti-Estrogen Effect of Iodine

Frederick R. Stoddard; Ari D. Brooks; Bernard A. Eskin; Gregg J. Johannes

International Journal of Medical Sciences ยท 2008

In plain language

In MCF-7 breast cancer cells, Lugol's iodine/iodide treatment altered expression of 43 genes, increasing estrogen-metabolizing genes CYP1A1, CYP1B1, and AKR1C1 while decreasing estrogen-responsive genes TFF1 and WISP2.

Evidence
Emerging
Design
Primary research (design unspecified)

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