Studies

CellWell record HH-131240

Perchlorate exposure and human health: Integrating biomonitoring evidence, thyroid mechanisms, and risk assessment

Michalak M; Fumery M; Bach V; Gay-Quéheillard J

The Science of the total environment · 2026

In plain language

This review synthesized biomonitoring and mechanistic evidence showing perchlorate competitively inhibits the sodium-iodide symporter, reducing thyroid hormone synthesis and potentially raising TSH, especially in pregnant and iodine-deficient populations.

Evidence
Emerging
Design
Expert review

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