Studies

CellWell record HH-122944

Breast Implant Illness and Autoimmune/Inflammatory Syndrome Induced by Adjuvants: Mechanistic Rationale and a Practical Multidisciplinary Diagnostic Algorithm

Velizar Shivarov; Angel Yordanov; Milena Ivanova; Eva Tsoneva

2026

In plain language

Breast implant illness describes systemic symptoms including fatigue, cognitive dysfunction, arthralgia, and myalgia potentially arising from chronic foreign-body inflammation, silicone gel bleed, macrophage activation, inflammasome signaling, cytokine dysregulation, and biofilm-derived metabolites.

Evidence
Emerging
Design
Expert review

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