Studies

CellWell record HH-121959

Critical Role of Iodine and Thyroid Hormones During Pregnancy

Rodrigo Moreno-Reyes; Camilo Fuentes Peña; Jonathan F Nuñez; María Belén Sánchez; Jonatan J Carvajal; Katherine Roble; María José Mendoza-León; Ma Andreina Rangel-Ramírez; Ma Cecilia Opazo; Margarita K Lay; Claudia A Riedel; Enrique Guzmán-Gutierrez; Juan Pablo Mackern-Oberti; Evelyn L Jara

2025

In plain language

Pregnancy increases iodine requirements via enhanced renal clearance, elevated thyroid hormone production, and transplacental transfer; mild deficiency causes maternal thyroid overstimulation, while severe deficiency results in fetal hypothyroidism with irreversible neurocognitive impairment.

Evidence
Emerging
Design
Expert review

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