Studies

CellWell record HH-12190

NRF2 pathway activation predicts poor prognosis in lung cancer: a cautionary note on antioxidant interventions.

Ungvari Z; Menyhart O; Lehoczki A; Fekete M; Fazekas-Pongor V; Ocana A; Varga P; Győrffy B

GeroScience · 2026

In plain language

An analysis of over 2,000 lung cancer patients found that higher tumor NRF2 pathway activation, the same antioxidant-defense pathway induced by sulforaphane, was associated with worse survival outcomes.

Studied in
Human

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