CellWell record HH-121343
An Optimization Approach for the Production of High-Purity Vitamin C‑Nicotinamide Cocrystals by the Gas Antisolvent (GAS) Technique with CO2 and Ethanol
Clóvis A Balbinot Filho; Thayli R Araujo; Jônatas L Dias; Evertan A Rebelatto; Adailton J Bortoluzzi; Mariana M Vernaschi; Tânia B Creczynski-Pasa; Sandra R S Ferreira; Marcelo Lanza
2026
In plain language
Vitamin C-nicotinamide cocrystals produced via gas antisolvent method with carbon dioxide achieved 99% purity and 85.2% yield while preserving ascorbic acid antioxidant capacity and thermal stability.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-121343
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