CellWell record HH-118817
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
Lucia A. de Jesus; Suzy D. Carvalho; Miriam O. Ribeiro; Mark J. Schneider; Sung Woo Kim; John W. Harney; P. Reed Larsen; Antônio C. Bianco
Journal of Clinical Investigation · 2001
In plain language
Type 2 deiodinase was essential for adaptive BAT thermogenesis, with D2 knockout mice becoming hypothermic due to impaired cAMP generation and UCP1 responsiveness.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-118817
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