Studies

CellWell record HH-104572

Effects of vitamin K2 and D3 supplementation on epicardial adipose tissue and systemic inflammation: A substudy of the AVADEC trial

Hasific S; Ravn EJ; Rasmussen LM; Mejldal A; Dey D; Frandsen NE; Lindholt JS; Auscher S; Lambrechtsen J; Hosbond S; Alan D; Urbonaviciene G; Becker S; Øvrehus KA; Diederichsen A

Atherosclerosis · 2025

In plain language

In 388 men aged 65-74 over 24 months, daily vitamin K2 (720 µg) and D3 (25 µg) significantly lowered markers of vitamin K deficiency but showed no effect on epicardial adipose tissue or systemic inflammation.

Evidence
Established
Design
Randomized controlled trial

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