Studies

CellWell record HH-104250

Beneficial effects of omega-3 and vitamin E coadministration on gene expression of SIRT1 and PGC1α and serum antioxidant enzymes in patients with coronary artery disease

Saboori S; Koohdani F; Nematipour E; Yousefi Rad E; Saboor-Yaraghi AA; Javanbakht MH; Eshraghian MR; Ramezani A; Djalali M

Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016

In plain language

In a randomized trial of 60 male coronary artery disease patients, adding vitamin E (400 IU/day) to omega-3 raised SIRT1 and PGC1alpha gene expression and total antioxidant capacity, suggesting combined effects on oxidative-stress and inflammation pathways.

Evidence
Established
Design
Randomized controlled trial

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