CellWell record HH-103132
Beyond Terminal Blockade: A Mechanism-Based Approach to Complement Inhibitor Selection in Paroxysmal Nocturnal Hemoglobinuria
Chang Chen; Jinman Zhong; Dan Xiong
2026
In plain language
A review of paroxysmal nocturnal hemoglobinuria found that terminal C5 complement inhibitors were linked to about an 80% lower blood clot risk in long-term data, while newer complement-blocking drugs have not been tested for that outcome.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-103132
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