Studies

CellWell record HH-102338

Tissue-specific role of hepcidin in iron homeostasis and innate immunity

Sara Zumerle

2026

In plain language

In mice, deleting hepcidin only in the liver caused the same iron overload as deleting it body-wide, and circulating hepcidin was undetectable, showing liver cells are the essential source of hepcidin controlling body iron that other tissues cannot replace.

Evidence
Emerging

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