CellWell record HH-102330
Phytochemical Modulation of Astrocyte A1/A2 Polarization and Hepcidin-Associated Iron Dysregulation in LPS-Driven Neuroinflammation
Masaki Kaneko; Chi-Fang Hsu; Cheng-Ta Tsai; Shion Osana; Takako Fujii; Susumu Ito; Katsuhiko Hata
2026
In plain language
In LPS-stimulated mouse astrocyte cultures, a multi-ingredient botanical blend markedly reduced hepcidin and ferritin heavy-chain gene expression and shifted astrocytes toward a neuroprotective marker profile, without changing the transferrin receptor, ferroportin, or BMP-SMAD pathway genes.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-102330
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