Studies

CellWell record HH-0464

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency

Ghosh A, Trivedi PP, Timbalia SA, Griffin AT, Rahn JJ, Chan SSL, Gohil VM

Human Molecular Genetics ยท 2014

In plain language

In a cellular model, copper supplementation restored assembly of cytochrome c oxidase, the terminal enzyme of the mitochondrial electron transport chain, illustrating copper's essential cofactor role in cellular energy production.

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